Andrea Marchione was a citizen of Genoa who was active during the first half of the fifteenth century. He was born the son of Girolamo Marchione held numerous offices in the civic administration during the 1430s, 1440s, and early 1450s. He served repeatedly as a councillor, with recorded terms in 1435, 1437, 1443, 1446, and 1448, and as an Elder (anziano) in 1437, 1440, 1447, and 1450. He also held financial and commercial offices, serving as an official of the Mint in 1437 and 1441 and as an official of Mercanzia in 1434 (probably) and again in 1449. In 1442 he acted as a partitor, while in 1443 he was appointed an official of La Spezia. The same record identifies him as a nobile bianco, and in 1449 as medio bianco, indicating his political affiliation within the Genoese factional system. In 1443 he suffered losses at Gavi at the hands of Pietro Fregoso and petitioned for compensation for these damages in the following year. He was again active in public affairs in 1451, when he is described as a bonvir. In 1456 his daughter Maria was attested as the spouse of Filippo Grimaldi by 1456.